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Capsule 133.3 mg 33.3 mg. lopinavir ritonavir LPVr Oral liquid 400 mg 100 mg5 ml. Tablet heat stable 100 mg 25 mg 200 mg 50 mg. Oral liquid 400 mg5 ml. ritonavir Solid oral dosage form 100 mg. Tablet heat stable 25 mg 100 mg. saquinavir SQV a Solid oral dosage form 200 mg. a25 kg. FIXEDDOSE COMBINATIONS lamivudine nevirapine stavudine lamivudine nevirapine zidovudine lamivudine zidovudine 2nd WHO Model List of Essential Medicines for Children March 2009 page 11Tablet 150 mg 200 mg 30 mg. Tablet dispersible 30 mg 50 mg 6 mg 60 mg 100 mg 12 mg. Tablet 30 mg 50 mg 60 mg 150 mg 200 mg 300 mg. Tablet 30 mg 60 mg 150 mg 300 mg. 6.4.3 Other antivirals Injection for intravenous administration 800 mg and 1 g in 10ml phosphate buffer solution. ribavirin Solid oral dosage form 200 mg 400 mg 600 mg. For the treatment of viral haemorrhagic fevers only. 6.5 Antiprotozoal medicines 6.5.1 Antiamoebic and antigiardiasis medicines Tablet 500 mg furoate. diloxanide a R a25 kg.R Review of effectiveness and safety for amoebiasis, with emphasis on comparative efficacy, safety, and age limits compared with oral paromomycin. Injection 500 mg in 100ml vial. metronidazole Oral liquid 200 mg as benzoate5 ml. Tablet 200 mg to 500 mg. 6.5.2 Antileishmaniasis medicines amphotericin B Powder for injection 50 mg in vial. As deoxycholate or liposomal. Solution for intramuscular injection 750 mg of paromomycin base present as the sulfate. Injection 100 mgml, 1 vial 30 ml or 30, equivalent to approximately 8.1 antimony in 5ml ampoule. RReview of comparative effectiveness and safety of antimonials for leishmaniasis, and whether they should be kept on the core list or moved to the complementary list. paromomycin sodium stibogluconate or meglumine antimoniate R 6.5.3 Antimalarial medicines 6.5.3.1 For curative treatment Medicines for the treatment of P. falciparum malaria cases should be used in combination. The list currently recommends combinations according to treatment guidelines. The Subcommittee recognizes that not all of these FDCs exist and encourages their development and rigorous testing. The Subcommittee also encourages development and testing of rectal dosage formulations. Tablet 153 mg or 200 mg as hydrochloride. amodiaquine To be used a in combination with artesunate 50 mg OR b may be used alone for the treatment of P.vivax, P.ovale and P.malariae infections. Oily injection 80 mgml in 1ml ampoule. For use in the management of severe malaria. Tablet 20 mg 120 mg. artemether lumefantrine Tablet dispersible 20 mg 120 mg. Not recommended in the first trimester of pregnancy or in children below 5 kg. 2nd WHO Model List of Essential Medicines for Children March 2009 page 12artemether Injection ampoules, containing 60 mg anhydrous artesunic acid with a separate ampoule of 5 sodium bicarbonate solution. For use in the management of severe malaria. artesunate Rectal dosage form 50 mg 200 mg capsules for prereferral treatment of severe malaria only patients should be taken to an appropriate health facility for followup care. Tablet 50 mg. To be used in combination with either amodiaquine, mefloquine or sulfadoxine pyrimethamine. Oral liquid 50 mg as phosphate or sulfate5 ml. chloroquine Tablet 100 mg 150 mg as phosphate or sulfate. For use only for the treatment of P.vivax infection. Capsule 100 mg as hydrochloride. doxycycline Tablet dispersible 100 mg as monohydrate. For use only in combination with quinine. mefloquine Tablet 250 mg as hydrochloride. To be used in combination with artesunate 50 mg. Tablet 7.5 mg 15 mg as diphosphate. primaquine Only for use to achieve radical cure of P.vivax and P.ovale infections, given for 14 days. Injection 300 mg quinine hydrochlorideml in 2ml ampoule. quinine Tablet 300 mg quinine sulfate or 300 mg quinine bisulfate. For use only in the management of severe malaria, and should be used in combination with doxycycline. sulfadoxine pyrimethamine 6.5.3.2 For prophylaxis Oral liquid 50 mg as phosphate or sulfate5 ml. chloroquine Tablet 150 mg as phosphate or sulfate. For use only for the treatment of P.vivax infection. doxycycline a Solid oral dosage form 100 mg as hydrochloride. a8 years. Tablet 500 mg 25 mg. Only in combination with artesunate 50 mg. mefloquine a Tablet 250 mg as hydrochloride. a5 kg or 3 months.proguanil Tablet 100 mg as hydrochloride. For use only in combination with chloroquine. 6.5.4 Antipneumocystosis and antitoxoplasmosis medicines pyrimethamine 2nd WHO Model List of Essential Medicines for Children March 2009 page 13Tablet 25 mg. sulfadiazine Tablet 500 mg. Injection sulfamethoxazole trimethoprim 80 mg 16 mgml in 5ml ampoule 80 mg 16 mgml in 10ml ampoule. Oral liquid 200 mg 40 mg5 ml. Tablet 100 mg 20 mg 400 mg 80 mg. 6.5.5 Antitrypanosomal medicines R R The Subcommittee requested a review of evidence for effectiveness and safety for medicines for trypanosomiasis in children. 6.5.5.1 African trypanosomiasis Medicines for the treatment of 1st stage African trypanosomiasis. Powder for injection 200 mg pentamidine isetionate in vial. pentamidine To be used for the treatment of Trypanosoma brucei gambiense infection. Powder for injection 1 g in vial. To be used for the treatment of the initial phase of Trypanosoma brucei rhodesiense infection. Medicines for the treatment of 2nd stage African trypanosomiasis eflornithine Injection 200 mg hydrochlorideml in 100ml bottle. To be used for the treatment of Trypanosoma brucei gambiense infection. melarsoprol Injection 3.6 solution in 5ml ampoule 180 mg of active compound.

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